The Subgenual Anterior Cingulate Cortex in Mood Disorders
نویسندگان
چکیده
منابع مشابه
The subgenual anterior cingulate cortex in mood disorders.
The anterior cingulate cortex (ACC) ventral to the genu of the corpus callosum has been implicated in the modulation of emotional behavior on the basis of neuroimaging studies in humans and lesion analyses in experimental animals. In a combined positron emission tomography/magnetic resonance imaging study of mood disorders, we demonstrated that the mean gray matter volume of this "subgenual" AC...
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Converging evidence suggests a central role for dysfunction of the subgenual anterior cingulate cortex (sgACC) in the pathophysiology of major depressive disorder (MDD). Underlying mechanisms may include altered GABAergic function. Expression of somatostatin (SST), an inhibitory neuropeptide localized to a subset of GABA neurons, has been shown to be lower in the dorsolateral prefrontal cortex ...
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OBJECTIVE Reduced deactivation within the default mode network (DMN) is common in individuals with primary affective disorders relative to healthy volunteers (HVs). It is unknown whether similar network abnormalities are present in temporal lobe epilepsy (TLE) patients with a history of affective psychopathology. METHODS 17 TLE patients with a lifetime affective diagnosis, 31 TLE patients wit...
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Mood disorders are among the most common neuropsychiatric illnesses, yet little is known about their neurobiology. Recent neuroimaging studies have found that the volume of the subgenual part of Brodmann's area 24 (sg24) is reduced in familial forms of major depressive disorder (MDD) and bipolar disorder (BD). In this histological study, we used unbiased stereological techniques to examine the ...
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Self-transcendence (ST) is one of specific human experiences often related to harmony with nature or feeling oneness with others or the self as an integral part of the whole universe. The Temperament and Character Inventory (TCI) is a widely used personality measure, and ST is one of personality dimensions (Cloninger, 1994; Cloninger et al., 1994). Previous studies showed that ST has significan...
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ژورنال
عنوان ژورنال: CNS Spectrums
سال: 2008
ISSN: 1092-8529,2165-6509
DOI: 10.1017/s1092852900013754